Association of IL23R p.381Gln and ATG16L1 p.197Ala With Crohn Disease in the Czech Population

Abstract

We confirmed the role of IL23R and ATG16L1 in the CD susceptibility in the Czech population, and found a weak protective effect of IL23R p.381Gln against upper gastrointestinal tract involvement.

Keywords

• ATG16L1
• Crohn's disease
• Genetic association
• IL23R
• inflammatory bowel disease
• susceptibility
• autophagy