APOE polymorphism as a potential determinant of functional fitness in the elderly regardless of nutritional status

Abstrakt

APOE gene polymorphism seems be an important genetic contributor to frailty development in the elderly. White APOE2 carriers tend to remain functionally fit till higher age, the functional status of APOE4 carriers deteriorates more rapidly.

Klíčová slova

• Apolipoprotein E
• life expectancy
• gene polymorphism
• functional fitness
• frailty