Biologic therapy in primary systemic vasculitis of the young

Abstract

To describe the biologic treatment regimens and report the efficacy and safety of biologic therapies in a multicentre series of children with primary systemic vasculitis. Our data provide retrospective evidence of efficacy of these agents, and highlight the associated infectious complications.

Further multicentre standardization of treatment protocols and data collection to inform clinical trials in this area is required.

Keywords

• Primary systemic vasculitis
• Children
• Biologic therapies
• Birmingham Vasculitis Activity Score
• Infection rate