Improvement in beta-cell function after diet-induced weight loss is associated with decrease in pancreatic polypeptide in subjects with type 2 diabetes

Abstract

The aim of our study was to evaluate the effect of a lifestyle intervention program on beta-cell function and to explore the role of gastrointestinal peptides in subjects with T2D.

Keywords

• Beta-cell function
• gut hormones
• pancreatic polypeptide
• pp-fold family
• insulin-resistance
• physical-activity
• obesity