Identification of a New Delhi metallo-beta-lactamase-4 (NDM-4)-producing Enterobacter cloacae from a Czech patient previously hospitalized in Sri Lanka
Abstrakt
Here, we describe an NDM-4-producing Enterobacter cloacae strain recovered from a patient previously hospitalized in Sri Lanka.We also present data on the localization and the genetic environment of the blaNDM-4 gene. To our knowledge, this is the first report of an NDM-producing Enterobacteriaceae described in Czech Republic, a country with low prevalence of carbapenemase-producing bacteria.
However, the patient was previously hospitalized in Sri Lanka, from where no epidemiological data focused on multidrug-resistant Gram-negative bacteria are available in international databases. Even though Sri Lanka belongs to a geographical region with high prevalence of NDM-producing isolates.
This is another report describing the impact of international traveling on the spread of antibiotic resistance, accelerated especially of repatriation of tourists that they were hospitalized in health-care settings with unknown epidemiological situation. The variability of the genetic environment of blaNDM genes further explains the observed rapid dissemination of these genes within various Gram-negative bacterial species worldwide.