Evaluation of serum levels of multiple cytokines and adhesion molecules in patients with newly diagnosed acute lymphoblastic leukemia using biochip array technology

Abstract

We evaluated serum levels of 17 cytokines and 5 adhesion molecules in patients with acute lymphoblastic leukemia (ALL) and in healthy subjects using biochip array technology. Our results indicate that serum levels of VCAM-1, ICAM-1, L-selectin, IL-8, IL-3, IL-4 and MCP-1 are significantly altered in patients with newly diagnosed ALL, reflecting activity of the disease. .

Keywords

• cytokines
• adhesion molecules
• biochip array
• acute lymphoblastic leukemia