Diclofenac sodium entrapment and release from halloysite nanotubules

Abstract

Diclofenac sodium was entraped into halloysite nanotubules; the drug release from halloysite nanotubules was prolonged. Halloysite itself as well as halloysite loaded with the drug proved to be appropriate material to form pellets by extrusion/spheronization method.

Keywords

• halloysite
• diclofenac sodium
• drug entrapment
• pellets
• prolonged drug release