Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid

Abstract

Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid

Keywords

• aristolochic acid
• carcinogen
• Aristolochic acid nephropathy
• Balkan endemic nephropathy
• detoxication
• HPLC
• balkan endemic nephropathy
• chinese herbs nephropathy
• urothelial cancer
• risk-factor
• reductive activation
• metabolic-activation
• etiology
• dna
• enzymes
• binding