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Fully solvated molecular dynamics simulations of a duplex formed by a modified oligonucleotide with the isosteric phosphonate internucleoside linkages and its natural counterpart

Publication at Faculty of Mathematics and Physics |
2000

Abstract

Fully solvated molecular dynamics simulations of a duplex formed by a modified oligonucleotide with the isosteric phosphonate internucleoside linkages and its natural counterpart