Free energy simulations of uncatalyzed DNA replication fidelity: Structure and stability of T.G and dTTP.G terminal DNA mismatches flanked by a single dangling nucleotide

Abstract

Free energy simulations of uncatalyzed DNA replication fidelity

Keywords

• binding-affinity prediction
• molecular-dynamics
• computer-simulation
• component analysis
• polymerase-beta
• decomposition
• mechanisms
• proteins