Investigation of vanadocene(IV) alpha-amino acid complexes: Synthesis, structure, and behavior in physiological solutions, human plasma, and blood

Abstract

This work is focused on investigating the interaction of antitumor active metallocene vanadocene dichloride (Cp2VCl2) and amino acids in aqueous solution at physiological pH.

Keywords

• organometallic anticancer agent
• drug titanocene dichloride
• renal-cell carcinoma
• antitumor agent
• metallocene dichlorides
• molybdocene dichloride
• coordination chemistry
• mechanistic implications
• escherichia-coli
• tumor-inhibition