Knock-down of mitochondrial iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei.

Abstract

Two mitochondrial proteins, the cysteine desulfurase TbiscS and the metallochaperone TbiscU are functionally conserved in trypanosomes and essential for this parasite

Keywords

• Parasitology
• mitochondrion
• FeS
• trypanosoma