Rare transformation in repeat renal biopsies suggests a different pathogenesis of segmental and global lesions in proliferative lupus nephritis

Abstract

Heterogenous histological findings in the renal biopsies of patients with systemic lupus erythematosus were distinguished early into different types of lupus nephritis with different outcomes. The effort to unify the terminolgy resulted in six clasess of the World Heatlh Organization (WHO) clasification published in 1982.

Keywords

• Proliferative lupus nephritis
• renal biopsies
• clinical presentation
• pathogenesis