Cytochromes P450 reconstituted with NADPH:P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes

Abstract

Activation and detoxication of the anticancer drug ellipticine by cytochromes P450 reconstituted with NADPH:P450 reductase

Keywords

• NADPH:P450 reductase
• ellipticine
• cytochromes P450
• metabolism