Publication at Faculty of Medicine in Hradec Králové |
2013
Abstract
Thrombotic diathesis is more than 50 years well known complication of oral contraceptive use. The risk is not only for venous thrombosis, but also for arterial one.
Etiology is usually a miltifactorial and depends on a several additional risk factors. We discuss the role of inherited thrombophilia with the focus on F V Leiden mutation and FII20210a mutation.
Hormonal contraception use belongs among very frequent causes of thrombosis in female in reproductive age. However, this risk is possible to decrease after appropriate assessment of all additional risk factors and due to thromboprophylaxis in risk situations.