Abstract
Extended set of visual evoked potentials (VEPs) using pattern-reversal (PREPs), linear motion-onset and radial (expansion) motion-onset stimuli (M-VEPs) was used to verify congenital stationary night-blindness (CSNB) characteristics in 7 patients (compared to 7 age matched controls) in photopic conditions (luminance of 17 cd/m2). No differences were found in any of the M-VEPs, whilst PREPs displayed prolonged latencies in 3 of 7 CSNB patients Additionally, the PREPs and M-VEPs were tested in 3 normal and 3 CSNB subjects over large range of scotopic, mesopic and photopic luminances (from 0.0001 to 65.4 cd/m2).
Both types of low luminance VEPs had distinctly increased luminance threshold needed for reliable VEPs eliciting in CSNB patients (0.06 cd/m2) when compared with controls (0.003 cd/m2). Thus, our pilot study proved that CSNB can be objectively detected also via scotopic VEP examination.