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Renal Tubular Dysfunction and Urinary Zinc Excretion in Breast Cance Patients Treated with Anthracycline-based Combination Chemotherapy

Publication at Faculty of Medicine in Hradec Králové |
2004

Abstract

The survival of breast cancer patients has significantly improved throug the treatment with anthracyclines. Although anthracyclines are known to produce renal disease in experimental animals, little is known about the toxicity of anthracyclines at clinically relevant doses in humans.