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BCL-2 protein and its role in the malignant transformation of cell

Publication at Central Library of Charles University, Faculty of Medicine in Hradec Králové |
2002

Abstract

Protein Bcl-2 localised in the intracellular membranes inhibits apoptosis-inducing adaptor proteins after the interaction with other proapoptotic proteins. Resulting defect in apoptosis could be the reason for the malignant transformation of cell.