How does lithium mediate its therapeutic effects?

Abstract

Lithium is an effective drug for the treatment of bipolar disorder. The effects of lithium on a number of enzymes and biological processes have been studied.

A therapeutic use for lithium in neurodegenerative disorders is discussed.

Keywords

• lithium
• bipolar disorder
• Alzheimer´s disease
• phosphoinositide signaling pathway
• inositol monophosphatase
• glycogen synthase kinase-3
• Wnt signaling
• lithium
• bipolární porucha
• Alzheimerova nemoc
• fosfoinositidy
• Wnt signalizace