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The difference in estradiol and cytokine concentrations after bile duct ligation in male and female rats

Publication at Faculty of Medicine in Hradec Králové |
2001

Abstract

Rats of both sex were estimated after bile duct ligation (BDL).Males after BDL had serum estradiol 119 pmol/l,but females had 669 pmol/l. Inhibitory effect of estradiol on IL-6 and TNF-alpha after BDL in female slowed induction of hepatic fibrosis