Contribution to the stereoselective synthesis of (3 ' S)-3 '-isothiocyanato-3 '-C-vinyl-3 '-deoxyuridine and its derivatives

Abstract

A stereoselective synthesis of the (3'S)-3'-isothiocyanato-3'-C-vinyl-3'-deoxyuridine via (3,3)sigmatropic rearrangement of allylic thiocyanate derived from protected uridine was investigated.

Keywords

• nucleoside analogs