Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: Evidence for its oxidative detoxication by human cytochromes P450

Abstract

The first report on the metabolism and detoxication of 2-nitroanisole by human P450 enzymes

Keywords

• DNA ADDUCT FORMATION
• ENVIRONMENTAL CONTAMINANT 3-NITROBENZANTHRONE
• CHINESE HERBS NEPHROPATHY
• RAT MAMMARY-GLAND
• REDUCTIVE ACTIVATION
• ARISTOLOCHIC ACIDS
• LIVER-MICROSOMES
• IN-VITRO
• SELECTIVE INHIBITORS
• NITROANISOLE