Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy-a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group

Abstract

Objectives: We aimed to provide a consensus statement by the International Rapid Eye Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active treatment studies in rapid eye movement sleep behavior disorder (RBD) and devising studies of neuroprotection against Parkinson disease (PD) and related neurodegeneration in RBD.

Keywords

• REM sleep behavior disorder
• RBD
• Treatment studies
• Clonazepam
• Melatonin
• Neuroprotective studies
• Parkinson disease
• PD
• alpha-Synucleinopathies
• Videopolysomnography