Publication
Abstract
Our aim was to evaluate the effect of four types of tissue scaffolds in a rabbit model of skin wound healing following 7, 14, and 21 days. We quantified the area fraction of type I collagen, foreign-bodies giant cells, the epidermis thickness and the microvessel density of actin-positive microvessels in the sesion as well as in the surrounding skin.
Our results suggest that the application of all types of tissue scaffolds resulted in a greater fraction of type I collagen and a smaller microvessel density when compared to lesions witout any scaffold.