TLR2 and TLR4 expression on blood monocytes and granulocytes of cardiac surgical patients is not affected by the use of cardiopulmonary bypass

Abstract

TLR2 and TLR4 expression is significantly modulated in patients undergoing coronary artery bypass grafting. The very surgical trauma is responsible for TLR2, 4 modulation.

Cardiopulmonary bypass itself was little contributing to the modulating of TLR2, 4 expression.

Keywords

• cardiac surgery
• inflammation
• TLR2 and TLR4 expression
• flow cytometry
• dynamics