Characterization of enzymes metabolizing aristolochic acid in human hepatic and renal cytosols.

Abstrakt

The results presented here are the first report demonstrating a reductive activation of carcinogenic AAI by human DT-diaphorese.

Klíčová slova

• Stiborová
• Marie 221951285 aristolochic acid
• CHN disease
• cytosol
• metabolic activation
• nephrotoxins
• reductases
• DT-diaphorese