The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency

Abstract

The anticancer drug ellipticine induces CYP1A1/2 enzymes in rats of both sexes and influences uts own CYP-dependent metabolism and activation.

Keywords

• Stiborová
• Marie 221951285 CYP1A1/2 activity
• EROD
• MROD
• ellipticine
• activation