The explanation of the inhibition effect of ellipticine on cytochromes P450

Abstract

Ellipticine binds with affinity greater than most other compounds known to interact with CYPs. All studied CYPs-specific reactions are inhibited by ellipticine, his inhibitory potential is non-specific.

Keywords

• Stiborová
• Marie 221951285 ellipticine
• microsomal CYP
• inhibition
• binding spectrum