Abstract
The aim of this study was to investigate the influence of galvanic cell on salivary immune defense factors. The levels of IgA1, IgA2, secretory IgA, lysozyme and antiIgA/HSP60 were evaluated in representative samples from 159 patients with galvanism, from 177 patients without galvanism and in two control groups.
All the participants underwent personal history taking, clinical examination, galvanic currents measurement and saliva collection. Electro active dental materials were removed in 30 patients.
There was a significant increase in IgA2 level, a significant decrease in antiIgA/HSP60 levels and an increase in IgA1, secretory IgA and lysozyme levels found after the removal of electro active restorations. Morphological symptoms disappeared in 70 % of the treated patients.
The study confirmed that pathologic galvanic phenomena influences the immune defense reactions in the oral cavity and thus deteriorates the symptoms of oral discomfort. A measurement of the galvanism and a subsequent removal of electro active restorations should become a common therapeutic procedure in the patients with oral discomfort.