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Other clinical applications of AMH in connection with the ovarian reserve

Publication at Faculty of Medicine in Pilsen |
2013

Abstract

Many studies have been performed on the topics of ovarian reserve, ovarian aging and on the prediction of the ovarian response to the hormonal stimulation involved in in vitro fertilization (IVF). The measurement of AMH serum levels is currently a useful tool in the examination of the ovarian reserve.

However, IVF is not the only reason for determination of AMH. The aim of this article is to present the topic of AMH from a different point of view.

Polycystic ovary syndrome (PCOS) is a big challenge not only for AMH examination but for the whole of medicine today. The relationship between AMH serum levels and antral follicle count (AFC) has been a very hot topic for medical discussion over the last few years.

AMH is a very sensitive tumor marker used in the diagnostics of ovarian granulosa cell tumors (GCTs). Cancer treatment places a burden on the entire organism, including healthy cells.

Follicles are very sensitive to radiation and chemotherapeutic agents. The changes in the number of follicles are monitored very sensitively using AMH serum levels.

Endometriosis has not the direct influence on the ovarian reserve and AMH serum levels.