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Treatment with a pump as the only successful solution in a patient with the type 1 diabetes mellitus and a coincidence and a coincident allergy to some insulin analogues

Publication at Second Faculty of Medicine |
2013

Abstract

Drug allergy , adverse reactions caused by the immunological response to said medicament. Although exact data on the number of people with type 1 type and current allergy medications do not exist, we can still meet people suffering from "multiple drug allergy syndrome" and therefore have had an immunological response to two or more chemically unrelated drugs.

Case report documents the search for the optimal form of treatment for patients with type 1 diabetes type and polyvalent allergy , which made ​​it impossible to use some insulin preparations. Making ጀ broindurativních deposits was accompanied by long-term administration of insulin analogues and attempt to insulin pump therapy in the past failed again on the inflammatory reaction around the Teflon cannula older generation.

She was therefore treated using human insulin in intensity ጀ forged regime, precisely Insuman Rapid and Insuman Basal , which tolerated with no reaction , but at the cost of high frequency of nocturnal hypoglycemic episodes. In order to change this unfavorable situation , we began gradually to test the tolerance of the individual components of insulin pump therapy ( a new generation of non-stick sets, insulin Humalog , etc. ).

After successfully testing the tolerance we started treatment with insulin bomb ( CSII ), which met expectations and effectively eliminate hypoglycemia. The slight decrease in HbA1c may be seen as a favorable response to treatment pump , like improving the quality of life of patients who have no fear of nocturnal hypoglycaemia .