Publikace na 1. lékařská fakulta |
2013
Abstrakt
Limited evidence is available about the early cardiac manifestation of Fabry disease (FD) in children. We aimed to evaluate cardiac involvement in children with FD by analysing serial structural and electrocardiographic changes.
The data were acquired from 22 children with FD. Seven patients (5 males) were on enzyme replacement therapy (ERT) with Agalasidase alpha.
Echocardiography, ECG and 24-h ECG monitoring recordings were acquired during routine annual clinical controls. ECG data were compared to a group of age-and gender-matched controls.