Abstract
Hodgkin lymphoma forms 8% of malignant tumours in childhood, it occurs most frequently between 15 and 19 years of age, with boys being relatively more frequently affected than girls. Clinical symptoms, histopathological classification and staging examinations are the same in children as in adult patients.
During the last 20 years, the children were treated according to national protocols which combined various chemotherapeutic regimens with involved field radiotherapy (IFRT). Current treatment protocols limit the doses of alkylating cytostatics due to late-onset complications and decrease the doses of radiotherapy as well.
Since the year 2007, children and adolescents with Hodgkin lymphoma are treated according to the EuroNet-PHL-Cl protocol in most European paediatric oncology centres.