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Dengue fever - epidemiology, diagnostics and new WHO classification

Publication at First Faculty of Medicine, Second Faculty of Medicine |
2013

Abstract

Dengue fever represents one of the most widely spread arthropod-borne diseases worldwide. The causative agents are four closely related serotypes of dengue virus, which belong to the family Flaviviridae.

Dengue fever affects approximately 50 to 100 million of people annually. In the endemic areas there is an estimated 2.5 billion people at risk of infection.

Approximately 80 million of travellers from developed countries arrive to these areas each year, thus dengue fever ranges among the most frequently imported febrile illnesses. The clinical course can be asymptomatic or presents as classic dengue fever or as severe disease leading to septic shock with haemorrhagic manifestations.

This case report describes dengue fever imported from Thailand. We describe the use of modern direct diagnostic methods, assessment of clinical course and presence of warning signs in accordance with new WHO guidelines (2009).