The regulatory region of Prague C v-Src inhibits the activity of the Schmidt-Ruppin A v-Src kinase domain-pY527 interaction.

Abstract

Low activity of v-src of Prague C strain of Raus sarcoma virus kinase is caused by mutations in SH3 domain rather than in kinase domain itself

Keywords

• Rous sarcoma virus
• oncogene
• molecular lock
• chimaera