Sudan I Is a Potential Carcinogen for Humans: Evidence for Its Metabolic Activation and Detoxication by Human Recombinant Cytochrome P450 1A1 and Liver Microsomes

Abstract

Oxidation of Sudan I by human cytochrome P450 1A1 is stimulated by microsomal cytochrome b5

Keywords

• 1-(Phenylazo)-2-naphthol
• azo compounds
• cytochrome b5
• metabolism
• cytochromes P450
• carcinogen