Leukaemia inhibitory factor (LIF) gene mutations in women diagnosed with unexplained infertility and endometriosis have a negative impact on the IVF outcome. A pilot study

Abstrakt

The frequency of functionally relevant mutations of the LIF gene in infertile women is significantly enhanced in comparison with fertile controls. In women with idiopathic infertility and endometriosis mutations have a negative impact on IVF outcome.