Inhibitory effect of FK 506 and cyclosporin A on nitric oxide production by LPS-treated cultured rat macrophages

Abstrakt

The effect of FK 506 and CsA on the production of nitric oxide by isolated peritoneal rat macrophages was analysed. FK 506 (0. 1 and 1 μg/ml) reduced the LPS-induced increase of NO2- levels by 68% and 81%, respectively.

CsA (0. 1 and 1 μg