Abstract
The diffusion of neuroactive substances in the CNS, which is the principle of the extrasynaptic transmission, is hindered by the cell swelling, formation of diffusion barriers by extracellular matrix molecules and astrogliosis.
The diffusion of neuroactive substances in the CNS, which is the principle of the extrasynaptic transmission, is hindered by the cell swelling, formation of diffusion barriers by extracellular matrix molecules and astrogliosis.