Objective: To compare Doppler flow Tei-indexes with standard intermittent transpulmonary thermodilution measurement with different hemodynamic loading conditions. Type of study: Experimental comparative study.
Materials and methods: Total 48 piglets (6 weeks old, average weight 23kg) under general anesthesia, were divided into groups under cardiac loading conditions (at rest, with increased left ventricular afterload, with increased right ventricular preload). At 60 and 120 minutes the animals were examined by echocardiography and simultaneously transpulmonary thermodilution was used to measure cardiac output.
Tei-indexes data were compared with invasively monitored haemodynamic data. Results: A total of 1632 parallel data were obtained.
Correlation was found between values of right Tei-index and changes in right ventricular preload (p<0.05) and afterload (p<0.01). Correlation was also found between left Tei-index values and changes of left ventricular preload (p<0.001), afterload (p<0.001), stroke volume (p<0.01), and cardiac output (p<0.01).
Conclusion: Tei-index as global myocardial performance selectively for the right and left ventricle can be recommended for monitoring of circulation and cardiac performance.