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Spatio Temporal Dynamics at rDNA Foci: Global Switching Between DNA Replication and Transcription

Publication at Faculty of Physical Education and Sport |
2005

Abstract

Fluorescence in situ hybridization (FISH) revealed numerous rDNA foci in the nucleolus. Each rDNA corresponds to a higher order chromatin domain containing multiple ribosomal genes.

Our results indicated that the rDNA foci are the functional un