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Isoprostanes: unique bioactive compounds as an index of endogenous lipid peroxidation

Publication at Third Faculty of Medicine |
2000

Abstract

The measurement of specific products of nonenzymatic lipid peroxidation, the F 2 "isoprostanes, appears to be a more accurate marker of oxidative stress in vivo in humans than other available met hods. The purpose of this review is to acquaint the reader with the isoprostanes from both a biochemic al perspective and available methods for their quantification as the marker of an endogenous lipid peroxidation.