Abstract
Undesireable reactions to local anesthetics occur in 2 - 3 % after their administration, but real allergic reactions appear in less than 1 % of all undesirable reactions, predominantly to anesthetics in the group of esters. Careful history and incremental challenge test using a local anesthetic usually can distinguish the true allergic reaction from other side effects.
Only one case of allergy to local anesthetics was proved in the group of 15 patients examined by exposure test.