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A case of canine insulinoma

Publication at Third Faculty of Medicine |
2004

Abstract

The paper reports on a ten-year-old German Shepherd presented with a history of episodic weakness and convulsions after exercise. The patient showed status epilepticus upon presentation.

Glucose concentrations repeatedly determined by glucometer were below detection threshold. After intravenous administration of glucose the condition always temporarily improved, however after 1-2 hours the situation reverted.

Insulinoma was diagnosed on the basis of parallel determination of hypoglycaemia (glucose 3.3 mmol(.)l(-1)) and hyperinsulinaemia (2.398 pmol(.)l(-1)). A poor prognosis was stated and the owner decided for euthanasia.

Necropsy revealed a tumour of pancreas. Subsequent pathological, immunohistochemical and electron microscopic examinations confirmed the diagnosis of insulinoma