Cognitive functions in unipolar depression are affected even after succesful treatment of depressive episode, during remission or fully recovery. Earlier understanding of cognitive deficits as pseudodementia, e.g. transition worsening of cognitive functions is at present replace by the idea of a long-term insufficiency of some aspects of cognitive functioning at least in some patients, which could not be dependent on extent and depths of illness alone.
Following changes of cognitive deficits, relationships to clinical and demographical variables could improve our understanding of variability or endurance of cognitive deficits and maybe, in the future, to support more directed terapeutical interventions to the patients. The project support monitoring of cognitive deficits at larger sample of patiens with unipolar depression through detailed neuropsychological assessment.