The study gives updated results of incidences analysis of both pre- and postnatally diagnosed birth defects in the Czech Republic until 2006. Some birth defect incidences in live birth are decreasing recently (neural tube defects, abdominal wall defects, Down syndrome), some are increasing (oesophageal defects, anorectal malformations).
Some incidences in births are influenced by an increased efficiency of diagnostics (renal defects) some remain more or less on the same level (diaphragmatic hernia) or just oscillate (facial defects).