Abstract
Aim of study: An analysis of occurrence of birth defects in the Czech Republic in 1994 - 2007. An assessment of total numbers and relative incidences of birth defects in births according to Tenth Revision of International Classification of Diseases (ICD-10).
Typ of study: Retrospective epidemiological analysis of birth defects incidences from the Czech National Birth Defects Register database. Material and methods: Data from the National Birth Defects Register (Institute for Health Information and Statistics) in the Czech Republic in the 1994 - 2007 period were used.
In this study, particular diagnoses - as they were registered in the National Register - were analyzed. The diagnoses in study were divided into following eleven birth defects groups according to ICD-10 classification: (Q00 - Q07) nervous system, (Q10 - Q18) eye, ear, face and neck, (Q20 - Q28) circulatory system, (Q30 - Q34) respiratory system, (Q35 - Q37) cleft lip and cleft palate, (Q38 - Q45) digestive system, (Q50 - Q56) genital organs, (Q60 - Q64) urinary system, (Q65 - Q79) musculoskeletal system, (Q80 - Q89) other defects and (Q90 - Q99) chromosomal abnormalities, not elsewhere classified.
Prenataly diagnosed cases are not included. Results: During 1994 - 2007 period, totally 1 353 040 children were born on the area of the Czech Republic, out of which 44 343 with a birth defect.
The diagoses in study were divided into eleven groups according to ICD-10 classification. Further, particular diagnoses according to ICD-10 and their verbal descriptions are presented in tables.
Each group is accompanied by data on its total number and a relative incidence (per 10 000 live births) with a 95% C.I.. A relative frequency of the birth defects groups in study (in % from the total number of birth defects) is as follows: (Q00 - Q07) nervous system 2.10, (Q10 - Q18) eye, ear, face and neck 4.76, (Q20 - Q28) circulatory system 39.63, (Q30 - Q34) respiratory system 1.03, (Q35 - Q37) cleft lip and cleft palate 3.67, (Q38 - Q45) digestive system 4.05, (Q50 - Q56) genital organs 10.93, (Q60 - Q64) urinary system 7.08, (Q65 - Q79) musculoskeletal system 18.90, (Q80 - Q89) other defects 5.55 and (Q90 - Q99) chromosomal abnormalities 2.28.
Conclusions: The study gives updated results of incidences analysis of postnatally diagnosed birth defects (available on the date of August 31, 2008) in the Czech Republic in the 1994 - 2007 period. Data on birth defects were collected in the National Birth Defects Register (Institute for Health Information and Statistics).
Birth defects registration is a compulsory process and is a part of the National Health Information System. The diagnoses in study were divided into eleven groups according to ICD-10 classification.
Total numbers, relative incidences (per 10 000 live births, with a 95% C.I.) and relative frequencies of the birth defects groups are presented.