Aim of study: An analysis of birth defects incidences in a co-incidence with children age tumors in the Czech Republic in 1994-2005. Some bio-social factors (maternal age, birth weight, gestational week at birth) and their roles were studied as well.
Conclusions: A higher risk of tumorigenesis in children with birth defect (compared to children without birth defect) was confirmed. There was also a lower survival in a group of children with tumor and birth defect compared to those with tumor and without birth defects.
A higher risk of tumorigenesis in some types of birt defects was also found.