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Differential Diagnosis of Allergic and Infectious Conjunctivitis

Publication at Central Library of Charles University, Third Faculty of Medicine |
2009

Abstract

Authors in this paper analyse problems of chronic follicular conjunctival inflammation and congeneric diseases from the aspects of allergic or infectious ethiology. All this diseases are associated with mostly mucopurulent secretion and major patient complains are itching, scratching and foreign body sensation.

Chronic follicular conjunctival transformation is accompanied by three clinical units of ocular allergy. Vernal conjunctivitis, and gigantopapillary conjunctivitis is characterised by different stage of upper tarsus transformation.

Clinical picture of chronic allergic conjunctivitis contains induration of lower transition plica of conjunctiva, increased tortuosity of veins and presence of follicles. Ligneous and flyktenous conjunctivitis are another rare conjunctival diseases with hyperplastic transformation of mainly bulbar conjunctiva.

This is a reaction to a non specified antigen. Ethiological agens of chronic conjunctivitis with follicular components cover up range of pathogens which are not primary linked to the conjunctiva.

It is especially gram-negative obligatory intracellular bacteria from the Chlamydia family. In our geographical region differential diagnosis for adult population contains paratrachoma (caused by Chlamydia trachomatis) and classic follicular conjunctivitis (caused by Chlamydia pneumonias).

Conjunctivitis caused by Chlamydia pneumoniae can be in addition accompanied by clinical picture of dry eye syndrome (keratoconjunctivitis sicca).