Implication of placenta-specific microRNAs in maternal circulation for diagnosis and prediction of placental insufficiency related complications
2010
Abstract
This article summarized the actual informations about presence of newly identified short non-coding RNAs, microRNAs, in peripheral blood of pregnant women. On the base of these informations the authors hypothesized that pregnancy complications related to placental insufficiency (preeclampsia and intrauterine growth restriction) could be characterized by unique profile of up-regulated and down-regulated placenta specific microRNAs, which could significantly differ between pregnancy with physiologic and pathologic course.